L1L2Signature is an implementation of an unbiased framework originally thought for gene expression analysis. The need of such a framework may be found in the Framework overview section illustrating the dramatic effect of a biased approach especially when the sample size is small.
The framework, here implemented, was used in many real applications and a collection of them is referenced in the Framework Applications section.
This library is composed by a set of Python scripts (described in the Quick start tutorial) and a set of useful classes and functions (described in the Public API section) that could be used to manually read and/or analyze high-throughput data extending/integrating the proposed pipeline.
L1L2Signature relies on two libraries also implemented by our research group and already released as open source libraries: